Mediclue Technology Pvt. Ltd.
CleanroomISO 14644-1ISPE Containment GuidelinesEU GMP Annex 1

Reverse Laminar Air Flow (RLAF)

Precision Airflow. Superior Protection.

Negative-pressure containment for potent compound dispensing & sampling.

Mediclue RLAF units provide operator and environment protection when handling potent, cytotoxic or highly active pharmaceutical ingredients. Inward airflow toward the HEPA exhaust creates a negative-pressure containment boundary that prevents cross-contamination during dispensing, sampling and weighing operations.

Key Features

  • Negative pressure containment — inward airflow direction
  • HEPA H14 exhaust filter with bag-in/bag-out capability
  • Continuous negative pressure monitoring with alarm
  • SS 316L smooth internal surfaces for easy decontamination
  • Glove port options and pass-through sample ports
  • Suitable for OEB3/OEB4 compounds

Applications

  • 01Potent compound dispensing and weighing
  • 02Cytotoxic drug manufacturing
  • 03High-containment sampling stations
  • 04API manufacturing in OEB3/4 environments

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Knowledge Center

Related Technical Resources

ValidationUnderstanding ISO 14644 Cleanroom Validation StandardsA practitioner's breakdown of particulate classification, recovery testing, and continuous monitorin…Read article →HVACOptimizing Air Flow in Pharmaceutical ManufacturingUnidirectional vs. turbulent airflow strategies for OSD, sterile fill-finish, and biologics suites —…Read article →

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